Wang Q, Ten Dijke P, Fan C. Deciphering the regulatory landscape of enhancer RNAs in health and disease. Signal Transduct Target Ther. 2026 Jan 29;11(1):29. doi: 10.1038/s41392-025-02436-z. PMID: 41605892.
Deciphering the Regulatory Landscape of Enhancer RNAs in Health and Disease
Please check our latest review by Chuannan Fan and Qian Wang to learn more about enhancer RNAs. These eRNA species contribute to complex and dynamic gene regulatory networks in both physiological and pathological conditions through diverse mechanisms. This review includes detailed sections on methods for detecting eRNAs, studying their functions, identifying interaction partners, and their role in transcriptional condensate formation. Furthermore, we propose future directions for advancing eRNA-based interventions in the treatment of human diseases.
