Gerbrand van der Heden van Noort from the Chemical Biology group will focus on the development of chemical tools to study dynamic post-translational modifications in detail. “The localization and activity of cellular proteins is regulated by dynamic posttranslational modifications. It turns out these modifications are also modified themselves, leading to a novel hidden layer of control." The researchers aim to develop chemical tools to study these complex processes in detail.
Good news for four experienced LUMC-researcher; they received a VIDI-grant of 800.000 from science financer NWO. Amongst them is CCB-scientist Gerbrand van der Heden van Noort who will use this grant to study the interplay between two post-translational modifications in detail using a novel chemical biology approach.