Intracellular bacteria, like Salmonella, are pathogens that enter, reside, and replicate inside the cells of their (human) host. This is possible because bacteria hijack intracellular molecular signals from the host. Virginie Stévenin will use the grant to investigate how Salmonella manipulates ubiquitin signaling to reshape the host cell organization as desired. Hence, Dr. Stévenin’s research line may reveal a new mechanism by which bacteria establish their intracellular replicative niche.
Virginie Stévenin of the Cell and Chemical Biology department of the LUMC has been awarded the prestigious Veni grant by the Netherlands Organization for Scientific Research (NWO).