Yingjie Zhong
RESEARCH:
I try to understand the molecular basis of the fusion of late endosomes or lysosomes with the plasma membrane, which is the last step during MHCII antigen presentation and exosome secretion. Using CRISPR/Cas9 based screening methodology, we have identified potential regulators of this fusion event, which is critical for immune activation and cancer metastasis. During my Ph.D, I will use cell biological tools to study the effect of candidate fusion regulators on membrane fusion, and exosome secretion and antigen presentation.
CURRICULUM VITAE:
After a bachelor in veterinary medicine. I obtained my Master degree from Institute of Animal Science, Chinese Academy of Agriculture Sciences. I mainly looked at the candidate genes affecting the variation of thoracic vertebrae number in sheep. I joined the Neefjes group as a PhD student to study the regulators of membrane fusion in September 2021.
