Drawing of Peter ten Dijke's Team

Chemical Immunology

Studying the basis of the immune system, bacterial infections and anti-cancer drugs.

Ubiquitin system chemistry & dynamics

Profiling the Ubiquitin-Proteasome System

Small Ubiquitin-like Modifiers

Uncovering signal transduction by SUMO

Ubiquitin signaling in DNA repair and cancer

Studying DNA repair- and cancer-relevant E3 enzymes specific targets

Chemical Signaling

Cell-to-cell communication via secreted factors, transmembrane receptors and intracellular signal transducers

Cell Signaling

Understanding TGF-ß- and MAP kinase-AP-1 pathways

Cell Signaling Dynamics

A window of opportunity: visualizing metastasis

Oncogenic Signaling in Melanoma

Molecular tumour genetics

Molecular cytogenetics and functional characterization of bone and soft tissue tumours

Transcriptional Regulation

DNA Replication & Repair

Molecular mechanisms of high-fidelity DNA replication

Genome Editing

Developing and integrating gene delivery and gene editing systems

Functional Genomics

Profiling the non-coding genome

Light and electron microscopy for biomedical applications

BioNanoPatterning

Bionanotechnology to probe immune system activation

Virus Cell Interactions

From innate sensing to oncolysis

Circadian Clocks

Investigating sleep regulation and sleep function

Cardiovascular Cell Biology

Where data science, virus and stem-cell biology is used to understand disease and develop therapeutics.

Diabetes Research

Molecular mechanisms of Type 1 and Type 2 Diabetes

Near patient diagnostics

High sensitivity diagnostic tools