PhD-student
Sudha Suriyamurthy
Research:
I am a PhD student in the laboratory of Prof. Peter ten Dijke. I am interested in deciphering the epigenetic modifications that takes place under the influence of TGF-β signaling in cancer. TGF-β pathway has a dichotomous role, it acts as a tumor suppressor in normal cells and a tumor promoter in more advanced cancers. My study will try to map the different epigenetic changes in breast cancer model system upon TGF-β treatment.
Curriculum Vitae:
I completed my Bachelor and Master degrees in Biotechnology from the University of Madras, India. Then, I worked as a research assistant in the National University of Singapore under the supervision of Prof. Reshma Taneja. I worked on characterizing the role of a lysine acetyl transferase, P/CAF in Pediatric cancer Alveolar Rhabdomyosarcoma. Since 2018, I joined the laboratory of Prof. Peter ten Dijke as a PhD student.
Publications
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P/CAF mediates PAX3–FOXO1-dependent oncogenesis in alveolar rhabdomyosarcoma
Bharathy, N*., Suriyamurthy, S*., Rao, V.K., Ow, J.R., Lim, H.J., Chakraborty, P., Vasudevan, M., Dhamne, C.A., Chang, K.T.E., Min, V.L.K., Kundu, T.K., Taneja, R.
The Journal of Pathology 240, 269–281. (2016)
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GLP inhibits heterochromatin clustering and myogenic differentiation by repressing MeCP2
Choi, M.H., Palanichamy Kala, M., Ow, J.R., Rao, V.K., Suriyamurthy, S., Taneja, R.,.
Journal of Molecular Cell Biology 10, 161–174. (2017)
Groups:
