About the Vertegaal lab

We are interested in unraveling signaling by SUMO, a ubiquitin-like modification predominantly found in nuclei of proliferating cells.   

The Vertegaal lab employs state-of-the-art mass spectrometry methods to probe post-translational modifications of proteins, with a focus on SUMO. Using the vast amount of data obtained from mass spectrometry experiments we pinpoint interesting targets and conduct further biochemical assays such as enzymatic in-vitro experiments, protein-protein interaction assays or advanced microscopy. Finally, we recapitulate our findings of molecular actions in relevant mouse models with the aim to translate our knowledge to clinical practice.


Collaborate with us

Looking for information on one of our topics, a new place to conduct your research or experienced research to join forces with?  Feel free to contact us.!

Read more