About the Vertegaal lab

We are interested in unraveling signaling by SUMO, a ubiquitin-like modification predominantly found in nuclei of proliferating cells.   

The Vertegaal lab employs state-of-the-art mass spectrometry methods to probe post-translational modifications of proteins, with a focus on SUMO. Using the vast amount of data obtained from mass spectrometry experiments we pinpoint interesting targets and conduct further biochemical assays such as enzymatic in-vitro experiments, protein-protein interaction assays or advanced microscopy. Finally, we recapitulate our findings of molecular actions in relevant mouse models with the aim to translate our knowledge to clinical practice.

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Looking for information on one of our topics, a new place to conduct your research or experienced research to join forces with?  Feel free to contact us.!

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