I am a post-doctoral scientist in the section Electron Microscopy in the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC). I am currently working as a post-doc in the Sharp lab where I develop DNA nanotechnology-based Bio-nanopatterning strategies to understand and exploit the human innate immune system.
I studied Life Science and Technology at the Universiteit Leiden and Technische Universiteit Delft. During this time I did internships in both the Soft Matter Chemistry group of Prof. Dr. Alexander Kros on the synthesis of covalent hydrogel materials for applications in drug release and in the Molecular Biotechnology group of Prof. Dr. Gilles van Wezel, where I did research on the role of cytoskeleton proteins in cell division and the possible existence of kinesins in Streptomyces coelicolor. In 2013, I started my Ph.D. research under Prof. Dr. Alexander Kros and Dr. Roxanne Kieltyka at the Supramolecular and Biomaterials Chemistry group of the Leiden Institute of Chemistry, Universiteit Leiden. Here I did research on the design and synthesis of supramolecular polymer materials for biomedical applications and diagnostics. I am currently working as a post-doc in the Sharp lab to develop DNA nanotechnology-based Bio-nanopatterning strategies to understand and exploit the human innate immune system.
Crosslinker‐Induced Effects on the Gelation Pathway of a Low Molecular Weight Hydrogel
Willem EM Noteborn, Damy NH Zwagerman, Victorio Saez Talens, Chandan Maity, Lars van der Mee, Jos M Poolman, Serhii Mytnyk, Jan H van Esch, Alexander Kros, Rienk Eelkema, Roxanne E Kieltyka
Advanced Materials (2017), 29 (12), 1603769
Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
Willem EM Noteborn, Victorio Saez Talens, Roxanne E Kieltyka
ChemBioChem (2018), 18 (20), 1995-1999
Grafting from a Hybrid DNA–Covalent Polymer by the Hybridization Chain Reaction
Willem EM Noteborn, Joeri AJ Wondergem, Anastasiia Iurchenko, Farhad Chariyev-Prinz, Dominique Donato, Ilja K Voets, Doris Heinrich, Roxanne E Kieltyka
Macromolecules (2018), 51 (14), 5157-5164