Dris El Atmioui
Research:
The main focus of my research in the group is the synthesis of peptides, mainly ubiquitin(like) and derivatives thereof. Besides the ubiquitin I synthesize specifically modified peptides like phosphorylated peptides, variations of the N-terminus (biotinylation, acetylation, fluorophores, etc), UV cleavable peptides and peptides with a side chain modification (such as thiolysine e.g.)
Publications
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Generation of the UFM1 Toolkit for Profiling UFM1-Specific Proteases and Ligases.
Witting KF, van der Heden van Noort GJ, Kofoed C, Talavera Ormeño C, El Atmioui D, Mulder MPC, Ovaa H.
Angew Chem Int Ed Engl. 2018 Oct 22;57(43):14164-14168.
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Total Chemical Synthesis of SUMO and SUMO-Based Probes for Profiling the Activity of SUMO-Specific Proteases.
Mulder MPC, Merkx R, Witting KF, Hameed DS, El Atmioui D, Lelieveld L, Liebelt F, Neefjes J, Berlin I, Vertegaal ACO, Ovaa H.
Angew Chem Int Ed Engl. 2018 Jul 16;57(29):8958-8962.
