PostDoc
Dr. MERVE ÖYKEN
RESEARCH:
I obtained my degrees in Biology. I gained Molecular Biology knowledge and experience in various techniques during my master and doctoral studies. I participated in a cancer genetics laboratory, focusing on characterization of breast cancer-related genes in terms of alternative polyadenylation. Currently, I have been working on finding ubiquitin system targets to stimulate Glucose Transporter 4 (GLUT4) trafficking and investigation of the role of Sorting Nexin 3 (SNX3) in Epidermal Growth Factor Receptor (EGFR) trafficking.
CURRICULUM VITAE:
I got my B.Sc. with honors in Biology from Middle East Technical University (METU) in June 2011. Then, I started my M.Sc. studies at METU in a breast cancer laboratory, focusing on miRNAs and alternative polyadenylation. I received my M.Sc. in February 2014 and then I continued my doctoral studies in the same lab, studied alternative polyadenylation and characterization of SNX3 in breast cancer. As part of a collaboration, I shortly joined the lab of Dr. Huib Ovaa in the LUMC during April-June 2019 (EMBO short-term fellowship). I obtained my PhD degree in January 2020 and I started in March 2020 as a post-doctoral fellow in the group of Dr. Huib Ovaa.
Publications
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Alternative Polyadenylation Patterns for Novel Gene Discovery and Classification in Cancer
Oguzhan Begik, Merve Oyken, Tuna Cinkilli Alican, Tolga Can, Ayse Elif Erson-Bensan
Neoplasia 2017 Jul;19(7):574-582. doi: 10.1016/j.neo.2017.04.008
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3'UTR shortening and EGF signaling: implications for breast cancer
Hesna Begum Akman, Merve Oyken, Taner Tuncer, Tolga Can, Ayse Elif Erson-Bensan
Hum Mol Genet 2015 Dec 15;24(24):6910-20. doi: 10.1093/hmg/ddv391
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ARID3B expression in primary breast cancers and breast cancer-derived cell lines
Ayse Selcen Oguz Erdogan, Nihan Ozdemirler, Merve Oyken, Murat Alper, Ayse Elif Erson-Bensan
Cell Oncol (Dordr) 2014 Aug;37(4):289-96. doi: 10.1007/s13402-014-0185-5.
