Yara Huppelschoten obtained her Bachelor´s degree in Chemistry at the Hogeschool Leiden, the Netherlands. During her bachelor, she performed a 9-month internship at the laboratory of Prof. Huib Ovaa at The Netherlands Cancer Institute. She worked on a variety of projects such as the synthesis of small molecules, chemical libraries and chemical probes. She also studied a minor in biopharmaceutical analysis, which got her interested in more than organic chemistry.
She therefore started a Master in Molecular Pharmacology at the Vrije Universiteit Amsterdam. She performed a 7-month internship at the laboratory of Prof. Rob Leurs, where she mainly focused on the pharmacological characterization of photoswitchable ligands for the histamine 3 receptor. Yara obtained her Master’s degree in August 2018, and moved to Copenhagen to pursue her PhD at Novo Nordisk.
Starting October 2022 Yara will continue her career in patent law.
Publications
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Total Chemical Synthesis of a Functionalized GFP Nanobody
Yara Huppelschoten, Angela F Elhebieshy, Dharjath S Hameed, Aysegul Sapmaz, Jens Buchardt, Thomas E Nielsen, Huib Ovaa, Gerbrand J van der Heden van Noort
ChemBioChem, 2022. PMID: 35920208
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State of the art in (semi-)synthesis of Ubiquitin- and Ubiquitin-like tools.
Huppelschoten Y, van der Heden van Noort GJ.
Semin Cell Dev Biol. 2021. PMID: 34961664
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Total Chemical Synthesis of LC3A and LC3B Activity-Based Probes
Yara Huppelschoten, Aysegul Sapmaz, Jens Buchardt, Thomas E. Nielsen, Gerbrand J. van der Heden van Noort
Biomedicines, 2023